Patanol Drug Uses

Patanol is a prescription medication that you can use to stop the affects off allergies in your daily life. Patanol is a liquid drop that you use in your eyes to keep your eyes from itching because of the allergies that you suffer from. Itchy eyes can cause redness, which will go away as you quit rubbing your eyes and your eyes are not itchy anymore because you are using Patanol.

How Taken

The recommended dose is one drop in each affected eye two times per day at an interval of 6 to 8 hours.

Patanol Warnings/Precautions

Do not use Patanol if you have a bacterial, viral, or fungal infection in your eye unless you are also receiving proper anti-infective treatment. Patanol is in the FDA pregnancy category C. This means that it is not known whether Patanol will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant. It is not known whether Patanol passes into breast milk. Do not use Patanol without first talking to your doctor if you are breast-feeding a baby. Patanol is not approved by the FDA for use by children younger than 3 years of age.

Patanol Missed Dose

Take the missed dose as soon as you remember it.

Patanol Possible Side Effects

Serious side effects from Patanol are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Less serious side effects may be more likely to occur. Continue to use Patanol and talk to your doctor if you experience burning, stinging, irritation, itching, redness, or dryness of the eyes; swollen eyelids; a stuffy or runny nose; headache; or changes in taste. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Patanol Storage

Store at 39°F to 86°F (4°C to 30°C).

Patanol Overdose

An overdose of this medication is unlikely to occur. If you do suspect an overdose, call an emergency room or poison control center near you. If the drops have been ingested (taken by mouth), drink plenty of fluid and call an emergency left for advice.

More Information

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye. Patanol contains a preservative (benzalkonium chloride), so do not wear contact lenses while applying this medication. Contact lenses can be inserted about 15 minutes after a dose. Avoid other eye drops unless your doctor approves.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Using Pitrakinra to inhibit interleukins-4 and -13 in the lungs may significantly reduce asthma symptoms, according to an article in the medical journal The Lancet, this week's issue.
The authors explain that doctors and scientists have believed for over twenty years that cytokines, such as interleukin-4 or interleukin-13 play a vital role in the onset and development of clinical asthma. However, there has been no scientific evidence that this might be so.
Dr Malinda Longphre, Aerovance Inc, Berkeley, California, USA and team carried out two separate Phase II clinical trials, where patients received Pitrakinra. In the first study 12 volunteers received 25mg of Pitrakinra by subcutaneous injection once per day. The patients in the second study were given either 60mg of Pitrakinra twice a day by nebulization, and another 16 received a placebo. In both trials the volunteers inhaled allergens before and four weeks after treatment - the allergens are designed to induce an asthma attack, the patient during an asthma attack of this type finds it harder to expel air.
The primary endpoint for the first trial was a maximum percentage drop in forced expiratory volume (FEV1)** in one second over 4-10 hours after receiving the allergen. In the second study the primary endpoint was average percentage fall in FEV1 over 4-10 hours after being given the allergen. If smaller falls in FEV1 during the asthma attack for the Pitrakinra group compared to the placebo group were detected, this would indicate that the allergic response had been reduced by Pitrakinra.
In the first study, say the researchers, the maximum percentage fall in FEV1 was 17.1% in the Pitrakinra and 23.1% in the placebo groups - a comparable difference of 26%. In the second study the average percentage drop in FEV1 was 4.4% in the Pitrakinra versus 15.9% in the placebo group - in other words, it was over three and a half times less in the Pitrakinra group.
"The effects of pitrakinra on late phase asthmatic response are promising when compared with similar studies with other successful anti-inflammatory asthma therapies...whether the effect is due to inhibition of interleukin-13 alone, or both interleukin-13 an interleukin-4, is not yet known. Future studies of this drug, as well as molecules that specifically inhibit interleukin-13, in asthmatic individuals of all levels of severity over longer periods of time are clearly warranted," the writers conclude.

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