Allegra D Drug Uses

Allegra-D is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 12 years of age and older. Symptoms treated effectively include sneezing, rhinorrhea, itchy nose/palate/ and/or throat, itchy/watery/red eyes, and nasal congestion.

How Taken

The recommended dose of Allegra-D is one tablet twice daily for adults and children 12 years of age and older. It is recommended that the administration of Allegra-D with food should be avoided. A dose of one tablet once daily is recommended as the starting dose in patients with decreased renal function.

Allegra D Warnings/Precautions

Do not take Allegra-D if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days; asthma or another lung disease; diabetes; thyroid problems; glaucoma or increased pressure in the eye; urinary retention or an enlarged prostate; kidney or liver disease; or heart disease, high blood pressure, or an irregular heartbeat. You may not be able to take Allegra-D, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Allegra-D is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take Allegra-D without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known if Allegra-D passes into breast milk. Do not take Allegra-D without first talking to your doctor if you are breast-feeding a baby. Allegra-D is not approved for use by children younger than 12 years of age.

Allegra D Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Allegra D Possible Side Effects

Nausea, stomach upset, trouble sleeping, headache, or cold symptoms may occur. If these persist or worsen, notify your doctor promptly. Unlikely but report promptly: dizziness, mental/mood changes, fast heartbeat, fever. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular heartbeat. Although drowsiness is very uncommon at usual doses under normal circumstances, be aware that drowsiness may occur and may affect the ability to perform tasks requiring alertness (e.g., driving). If you notice other effects not listed above, contact your doctor or pharmacist.

Allegra D Storage

Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from sunlight and moisture.

Allegra D Overdose

In large doses, Allegra-D may give rise to giddiness, headache, nausea, vomiting, sweating, thirst, tachycardia, precordial pain, palpitations, difficulty in micturition, muscular weakness and tenseness, anxiety, restlessness, and insomnia. You can present a toxic psychosis with delusions and hallucinations or you may develop cardiac arrhythmias, circulatory collapse, convulsions, coma, and respiratory failure.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Allegra-D may cause dizziness. If you experience dizziness, avoid these activities. Do not take Allegra-D close to a dose of an antacid that contains aluminum or magnesium. These antacids may decrease the effects of Allegra-D.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Singulair® (Montelukast), launched in the UK in February 1998, is a new once daily tablet treatment for asthma. There is a chewable tablet for children aged 6 to 15 years.
Together with zafirlukast, it is new kind of treatment for asthma, and works by blocking the effect of substances called leukotrienes, which are important in asthma.
Montelukast is an add-on treatment which improves the health of people with asthma who are already using inhaled steroid 'preventer' treatments but are not getting enough help from those and the other usual treatments.
How does montelukast work?
Montelukast is one of a group of new drugs which work by blocking the effect of an important group of substances released in the lungs during the process which leads to asthma. These substances are called leukotrienes. Just as antihistamines stop a substance called histamine from working, so montelukast stops leukotrienes from working.
Leukotrienes are important in asthma because their release from cells in the lungs causes narrowing of the air passages, for example by making the muscles around the air tubes contract. So one benefit of montelukast is that it acts against this muscle contraction, and so against narrowing of the air passages.
But leukotrienes act in quite a number of ways to help produce asthma. We now know that in asthma the air tubes are not just narrowed by contracting muscle fibres, but that the lining membrane of the air tubes is inflamed, looking red in colour. The microscope shows that the inflamed lining membrane is also full of cells we normally think of as white blood cells, including cells called eosinophils. Over the longer run these cells cause damage in the lungs, which is why older people with asthma generally don't get such good results from treatment as younger people. Leukotrienes play an important part in bringing about this inflammation, and montelukast should help alsthma in the longer term by helping to minimise inflammation and the damage it causes.
How well does it work in practice?
Careful trials on large numbers of patients showed that, in some groups of people with asthma, montelukast reduced night-time asthma attacks as well as attacks and poor control during the daytime. Regular use also reduced the number of times people needed to use steroid tablets because the asthma went out of control.
Some people claim that montelukast may be specially useful for some kinds of asthma, such as asthma brought on by exercise or by aspirin.
Time will tell how much montelukast will contribute to the life of people who have asthma. It seems that we are not looking at a dramatic cure, but at a medicine which will make a very positive difference for many people.

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